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PTGER2 Antibody

Product Specifications

Gene Aliases

EP2

Gene ID

5732

Swiss Prot

P43116

Accession Number

NP_000947

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human PTGER2.

Target

This gene encodes a receptor for prostaglandin E2, a metabolite of arachidonic acid which has different biologic activities in a wide range of tissues. Mutations in this gene are associated with aspirin-induced susceptibility to asthma. Prostaglandin E2 receptor (53kDa), also known as EP2, is a prostaglandin receptor for prostaglandin E2. It is encoded by the human gene PTGER2. Receptor for prostaglandin E2 (PGE2) . The activity of this receptor is mediated by G (s) proteins that stimulate adenylate cyclase. The subsequent raise in intracellular cAMP is responsible for the relaxing effect of this receptor on smooth muscle.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

The antiserum was purified by peptide affinity chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/mL

Format

Liquid.// PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol

Reconstitution

Store at -20C. Stable for 12 months from date of receipt._x005F

Molecular Weight

40 kDa

Fragment

IgG

Specificity

PTGER2 Ab detects endogenous levels of total PTGER2

NCBI Gene Symbol

PTGER2

Host or Source

Rabbit

Protein Name

Prostaglandin E2 receptor EP2 subtype

Gene Name URL

PTGER2

CAS Number

9007-83-4

Nucleotide Accession Number

NM_000956

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