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DNMT3L Antibody

Product Specifications

CAS Number

9007-83-4

Gene Aliases

DNA (cytosine-5) -methyltransferase 3-like, MGC1090

Gene ID

29947

Swiss Prot

Q9UJW3

Accession Number

NP_037501

Reactivity

Human, Mouse

Immunogen

Recombinant proteinof human DNMT3L

Target

Catalytically inactive regulatory factor of DNA methyltransferases. It is essential for the function of DNMT3A and DNMT3B. Activates DNMT3A and DNMT3B by binding to their catalytic domain. Accelerates the binding of DNA and AdoMet to the methyltransferases and dissociates from the complex after DNA binding to the methyltransferases. Recognizes unmethylated histone H3 lysine 4 (H3K4) and induces de novo DNA methylation by recruitment or activation of DNMT3.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB, IHC, IF, IP, CHIP

Purification

Immunogen affinity chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/mL

Format

Liquid

Reconstitution

Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.

Molecular Weight

44 kDa

NCBI Gene Symbol

DNMT3L

Host or Source

Rabbit

Protein Name

DNA (cytosine-5) -methyltransferase 3-like

Gene Name URL

DNMT3L

Nucleotide Accession Number

NM_013369

Frequently Asked Questions

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