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ANG Antibody

Product Specifications

CAS Number

9007-83-4

Gene Aliases

ALS9, RAA1, HEL168, RNASE4, RNASE5

Gene ID

283

Swiss Prot

P03950

Accession Number

NP_001091046

Reactivity

Human, Mouse, Rat

Immunogen

Recombinant proteinof human ANG

Target

Binds to actin on the surface of endothelial cells; once bound, angiogenin is endocytosed and translocated to the nucleus. Stimulates ribosomal RNA synthesis including that containing the initiation site sequences of 45S rRNA. Cleaves tRNA within anticodon loops to produce tRNA-derived stress-induced fragments (tiRNAs) which inhibit protein synthesis and triggers the assembly of stress granules (SGs) . Angiogenin induces vascularization of normal and malignant tissues. Angiogenic activity is regulated by interaction with RNH1 in vivo.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Immunogen affinity chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/mL

Format

Liquid

Reconstitution

Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.

Molecular Weight

17 kDa

NCBI Gene Symbol

ANG

Host or Source

Rabbit

Protein Name

Angiogenin

Gene Name URL

ANG

Nucleotide Accession Number

NM_001097577

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