CCND2 Antibody (Phospho-Thr280)

Product Specifications

CAS Number

9007-83-4

Gene Aliases

MPPH3, KIAK0002

Gene ID

894

Swiss Prot

P30279

Accession Number

NP_001750

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Cyclin D2 (Phospho-Thr280)

Target

Regulatory component of the cyclin D2-CDK4 (DC) complex that phosphorylates and inhibits members of the retinoblastoma (RB) protein family including RB1 and regulates the cell-cycle during G1/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complex and the subsequent transcription of E2F target genes which are responsible for the progression through the G1 phase.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB, ICC, IF, P-ELISA

Purification

The Ab is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/mL

Format

Liquid// PBS (pH 7.4), 150mM NaCl, 0.02% sodium azide and 50% glycerol

Reconstitution

Store at -20° C. Stable for 12 months from date of receipt.

Molecular Weight

33 kDa

Fragment

IgG

Specificity

Cyclin D2 (Phospho-Thr280) Ab detects endogenous levels of total Cyclin D2 (Phospho-Thr280)

NCBI Gene Symbol

CCND2

Host or Source

Rabbit

Protein Name

G1/S-specific cyclin-D2

Gene Name URL

CCND2

Nucleotide Accession Number

NM_001759

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