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MRGPRX1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Aliases

GPCR, MGRG2, MRGX1, SNSR4

Gene ID

259249

Swiss Prot

Q96LB2

Accession Number

NP_671732

Reactivity

Human

Immunogen

A synthesized peptide

Target

Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22) (PubMed:26582731) . BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G (alpha) q proteins are involved in the calcium-signaling pathway. Activated by the antimalarial drug, chloroquine. May mediate chloroquine-induced itch, in a histamine-independent manner.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB, IF, ICC

Purification

Immunogen affinity chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/mL

Format

Liquid

Reconstitution

Store at +4C. For long term storage, aliquot and store at -20C. Avoid freeze/thaw cycles.

Molecular Weight

36 kDa

NCBI Gene Symbol

MRGPRX1

Host or Source

Rabbit

Protein Name

Mas-related G-protein coupled receptor member X1

Gene Name URL

MRGPRX1

Nucleotide Accession Number

NM_147199

Frequently Asked Questions

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