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CYP4F11 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Aliases

CYPIVF11

Gene ID

57834

Swiss Prot

Q9HBI6

Accession Number

NP_001122404

Reactivity

Human

Immunogen

A synthesized peptide derived from human Cytochrome P450 4F11, corresponding to a region within C-terminal amino acids.

Target

Omega-hydroxylase that oxidizes a variety of structurally unrelated compounds, including fatty acids and xenobiotics. Plays a key role in vitamin K catabolism by mediating omega-hydroxylation of vitamin K1 (phylloquinone), and menaquinone-4 (MK-4), a form of vitamin K2. Hydroxylation of phylloquinone and MK-4 probably regulates blood coagulation. Catalyzes omega-hydroxylation of 3-hydroxy fatty acids, such as 3-hydroxypalmitate, 3-hydroxyoleate, 3-hydroxyarachidonate, and 3-hydroxystearate. Oxidizes drugs such as erythromycin, benzphetamine, ethylmorphine, chlorpromazine and imipramine.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB, IF, ICC, P-ELISA

Purification

Peptide affinity chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/mL

Format

Liquid// PBS (pH 7.4), 150mM NaCl, 0.02% sodium azide and 50% glycerol

Reconstitution

Store at -20° C. Stable for 12 months from date of receipt.

Molecular Weight

60 kDa

Fragment

IgG

Specificity

Cytochrome P450 4F11 Antibody detects endogenous levels of total Cytochrome P450 4F11.

NCBI Gene Symbol

CYP4F11

Host or Source

Rabbit

Protein Name

Phylloquinone omega-hydroxylase CYP4F11

Gene Name URL

CYP4F11

Nucleotide Accession Number

NM_001128932

Frequently Asked Questions

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