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TIMP1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

TIMP metallopeptidase inhibitor 1

Gene Aliases

EPA, EPO, HCI, CLGI, TIMP, TIMP-1

Gene ID

7076

Swiss Prot

P01033

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human TIMP1, corresponding to a region within the internal amino acids

Target

TIMP1 Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. Also mediates erythropoiesis in vitro; but, unlike IL-3, it is species-specific, stimulating the growth and differentiation of only human and murine erythroid progenitors. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-10, MMP-11, MMP-12, MMP-13 and MMP-16.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB, IF, ICC, IHC, P-ELISA

Purification

Purified by peptide affinity chromatography

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid.// PBS, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Molecular Weight

24 kDa

Fragment

IgG

Specificity

TIMP1 antibody detects endogenous levels of total TIMP1

NCBI Gene Symbol

TIMP1

Host or Source

Rabbit

Gene Name URL

TIMP1

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