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TSC1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Tuberous sclerosis 1

Gene Aliases

LAM, TSC

Gene ID

7248

Swiss Prot

Q92574

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide

Target

In complex with TSC2, inhibits the nutrient-mediated or growth factor-stimulated phosphorylation of S6K1 and EIF4EBP1 by negatively regulating mTORC1 signaling. Seems not to be required for TSC2 GAP activity towards RHEB. Implicated as a tumor suppressor. Involved in microtubule-mediated protein transport, but this seems to be due to unregulated mTOR signaling.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB, IHC

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. PBS, pH 7.4, 50% glycerol.

Reconstitution

Store at -20C. Stable for 12 months from date of receipt.

Molecular Weight

150-170 kDa

Specificity

TSC1 antibody detects endogenous levels of total TSC1

NCBI Gene Symbol

TSC1

Host or Source

Rabbit

Gene Name URL

TSC1

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