SIRT1 Antibody (Phospho-Ser47)
Product Specifications
CAS Number
9007-83-4
Gene Name
Sirtuin 1
Gene Aliases
SIR2, SIR2L1, SIR2alpha
Gene ID
23411
Swiss Prot
Q96EB6
Reactivity
Human, Mouse
Immunogen
A synthesized peptide derived from human SirT1 around the phosphorylation site of Serine 47
Target
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
WB
Purification
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho- and non-phospho-peptide affinity columns.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid.// PBS (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Reconstitution
Stable at -20° C for at least 1 year.
Molecular Weight
110 kDa
Fragment
IgG
Specificity
Phospho-SirT1 (Ser47) antibody detects endogenous levels of SirT1 only when phosphorylated at Serine 47.
NCBI Gene Symbol
SIRT1
Host or Source
Rabbit
Gene Name URL
SIRT1
Frequently Asked Questions
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