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MAP2K3 Antibody (Phospho-Ser189)

Product Specifications

CAS Number

9007-83-4

Gene Name

Mitogen-activated protein kinase kinase 3

Gene Aliases

MEK3, MKK3, MAPKK3, PRKMK3, SAPKK2, SAPKK-2

Gene ID

5606

Swiss Prot

P46734

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human MKK3 around the phosphorylation site of Serine 189

Target

The protein encoded by this gene is a dual specificity protein kinase that belongs to the MAP kinase kinase family. This kinase is activated by mitogenic and environmental stress, and participates in the MAP kinase-mediated signaling cascade. It phosphorylates and thus activates MAPK14/p38-MAPK. This kinase can be activated by insulin, and is necessary for the expression of glucose transporter.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Immunogen affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Reconstitution

Store at -20C. Stable for 12 months from date of receipt.

Molecular Weight

40 kDa

Specificity

Phospho-MKK3 (Ser189) antibody detects endogenous levels of MKK3 only when phosphorylated at Serine 189

NCBI Gene Symbol

MAP2K3

Host or Source

Rabbit

Gene Name URL

MAP2K3

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