Lamin A/C Antibody (Phospho-Ser392)
Product Specifications
CAS Number
9007-83-4
Gene Name
Lamin A/C
Gene Aliases
FPL, IDC, LFP, CDDC, EMD2, FPLD, HGPS, LDP1, LMN1, LMNC, MADA, PRO1, CDCD1, CMD1A, FPLD2, LMNL1, CMT2B1, LGMD1B
Gene ID
4000
Swiss Prot
P02545
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human Lamin A/C around the phosphorylation site of Serine 392
Target
The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated.
Clonality
Polyclonal
Type
Polyclonal Antibody
Source
Rabbit
Applications
WB, IHC, IF, ICC, P-ELISA
Purification
The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1 mg/ml
Format
Liquid// PBS (pH 7.4) 150mM NaCl, 0.02% sodium azide and 50% glycerol
Reconstitution
Store at -20° C. Stable for 12 months from date of receipt.
Molecular Weight
74 kDa, 65 kDa
Fragment
IgG
Specificity
Phospho-Lamin A/C (Ser392) antibody detects endogenous levels of Lamin A/C only when phosphorylated at Serine 392
NCBI Gene Symbol
LMNA
Host or Source
Rabbit
Gene Name URL
LMNA
Frequently Asked Questions
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