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Lamin A/C Antibody (Phospho-Ser392)

Product Specifications

CAS Number

9007-83-4

Gene Name

Lamin A/C

Gene Aliases

FPL, IDC, LFP, CDDC, EMD2, FPLD, HGPS, LDP1, LMN1, LMNC, MADA, PRO1, CDCD1, CMD1A, FPLD2, LMNL1, CMT2B1, LGMD1B

Gene ID

4000

Swiss Prot

P02545

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human Lamin A/C around the phosphorylation site of Serine 392

Target

The nuclear lamina consists of a two-dimensional matrix of proteins located next to the inner nuclear membrane. The lamin family of proteins make up the matrix and are highly conserved in evolution. During mitosis, the lamina matrix is reversibly disassembled as the lamin proteins are phosphorylated.

Clonality

Polyclonal

Type

Polyclonal Antibody

Source

Rabbit

Applications

WB, IHC, IF, ICC, P-ELISA

Purification

The antibody is from purified rabbit serum by affinity purification via sequential chromatography on phospho-peptide and non-phospho-peptide affinity columns.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid// PBS (pH 7.4) 150mM NaCl, 0.02% sodium azide and 50% glycerol

Reconstitution

Store at -20° C. Stable for 12 months from date of receipt.

Molecular Weight

74 kDa, 65 kDa

Fragment

IgG

Specificity

Phospho-Lamin A/C (Ser392) antibody detects endogenous levels of Lamin A/C only when phosphorylated at Serine 392

NCBI Gene Symbol

LMNA

Host or Source

Rabbit

Gene Name URL

LMNA

Frequently Asked Questions

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