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CHUK Antibody (Phospho-Ser176/Ser177)

Product Specifications

CAS Number

9007-83-4

Gene Name

Conserved helix-loop-helix ubiquitous kinase

Gene Aliases

IKK1, IKKA, IKBKA, TCF16, NFKBIKA, IKK-alpha

Gene ID

1147

Swiss Prot

O15111

Reactivity

Human, Mouse, Rat

Immunogen

A synthesized peptide derived from human IKK- alpha /IKK- beta around the phosphorylation site of Serine 177

Target

IKK-beta a kinase of the IKK family. Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. Preferentially found as a heterodimer with IKK-alpha but also as an homodimer.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

WB, IHC

Purification

Immunogen affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Format

Liquid. Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Reconstitution

Store at -20C. Stable for 12 months from date of receipt.

Molecular Weight

85 kDa

Specificity

Phospho-IKK- alpha (Ser176) /IKK- beta (Ser177) antibody detects endogenous levels of IKK- alpha /IKK- beta only when phosphorylated at Serine 177

NCBI Gene Symbol

CHUK

Host or Source

Rabbit

Gene Name URL

CHUK

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