Anti-GLEPP-1 Antibody

GLEPP1; glomerular epithelial protein 1; NPHS6; osteoclastic transmembrane protein-tyrosine phosphatase; phosphotyrosine phosphatase U2; protein tyrosine phosphatase PTP-U2; PTP phi; PTPase U2; PTP-OC; PTPROT; PTPU2; PTP-U2; receptor-type tyrosine-protein phosphatase O; R-PTP-O.

Glomerular Epithelial Protein 1 (GLEPP-1) is a transmembrane protein tyrosine phosphatase found only in the epithelial cells of the renal glomerulus. It is localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. It may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppresor, and decreased expression of this gene has been observed in several types of cancer. GLEPP-1 is present only in visceral glomerular cells (Podocytes) . The presence of GLEPP1 may be used as a marker of podocyte integrity in various forms of glomerular injury.

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.