What is the catalog number for Desmin Antibody (Paired T76/77) Non-phospho?

The catalog number for Desmin Antibody (Paired T76/77) Non-phospho is OAAI00566-100UG.

What sizes are available for Desmin Antibody (Paired T76/77) Non-phospho?

Desmin Antibody (Paired T76/77) Non-phospho is available in the following size(s): 100 µg.

Is Desmin Antibody (Paired T76/77) Non-phospho in stock?

Desmin Antibody (Paired T76/77) Non-phospho is currently made to order / not held in immediate stock. Contact us for lead time.

Is there an additional fee for hazardous or dry ice shipping of this product?

Yes, if this product requires dry ice or is classed as hazardous for transport, the additional fee will be explicitly shown in your quotation before you confirm the order, so there are no surprise charges later.

How many freeze-thaw cycles can this product tolerate?

We recommend aliquoting the product upon receipt to avoid repeated freeze-thaw cycles, which can reduce activity and stability. This is your responsibility once the product has been delivered.

Is antigen retrieval required for IHC with this antibody?

Recommended antigen retrieval methods, where applicable, are listed on the datasheet under the IHC protocol section.

Desmin Antibody (Paired T76/77) Non-phospho

Product Specifications

CAS Number

9007-83-4

Gene Name

Desmin

Gene Aliases

Cardiomyopathy, dilated 1F (autosomal dominant) ; CDCD3; CSM1; CSM2; desmin; epididymis secretory sperm binding protein; intermediate filament protein; LGMD1D; LGMD1E; LGMD2R.

Gene ID

1674

Swiss Prot

P17661

Reactivity

Human|Mouse|Rat

Immunogen

A synthetic peptide corresponding to the N-terminus surrounding Threonine (Thr76/Thr77) without phosphorylation of human Desmin

Target

Desmin is a major intermediate filament protein found exclusively in striated (skeletal or cardiac) muscle tissue. It belongs to a large family of class III intermediate filament protein, the main intermediate filamentin mature skeletal, cardiac and smooth muscle cells. Mutations in the gene encoding desmin are associated with desmin-related myopathy, a familial cardiac and skeletal myopathy (CSM), and with distal myopathies. PKC (Protein Kinase C) and cAMP-dependent protein kinase can induce disassembly of the desmin filaments by phosphorylating multiple sites at N-terminus of desmin which can affect the desmin filament structure which play a role in the regulatory process in assembly and turnover.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Flow cytometry|Immunohistochemistry|Immunoprecipitation|Western blot

Purification

Affinity Purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

100ug/200ul

Format

Liquid. This affinity purified antibody is supplied in sterile Phosphatebuffered saline (pH7.2) containing antibody stabilizer

Reconstitution

The antibodies are stable for 24 months from date of receipt when stored at -20C to -70C. The antibodies can be stored at 2C-8C for three month without detectable loss of activity. Avoid repeated freezing-thawing cycles.