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CCNE1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

G1/S-specific cyclin-E1

Gene Aliases

CCNE, pCCNE1

Gene ID

898

Swiss Prot

P24864

Accession Number

NP_001229.1XP_006723520.1

Immunogen

Cyclin E1 polyclonal antibody is produced by immunizing rabbit with asynthetic peptide derived from human Cyclin E1

Target

Cyclin E is a regulatory subunit of cdk-2 and controls G1/S transition during the mammalian cell cycle. Multiple isoforms of cyclin E are expressed only in tumors but not in the normal tissues, suggesting a post-transcriptional regulation of cyclin E. In vitro analyses indicated that these truncated variant isoforms of cyclin E are able to phosphorylate histone H1. Alterations in cyclin E protein have been implicated as indicators of worse prognosis in various cancers.

Clonality

Polyclonal

Type

Polyclonal Antibody

Source

Rabbit pAb

Applications

WB

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Reconstitution

Store the product at -20C. Stable for one year from the date of shipment.

Molecular Weight

47 kDa

Fragment

Rabbit lgG

Specificity

Cyclin E1 polyclonal antibody detects endogenous levels of total Cyclin E1 protein

Protein Length

410

NCBI Gene Symbol

CCNE1

Host or Source

Rabbit

Protein Name

G1/S-specific cyclin-E1

Gene Name URL

CCNE1

Nucleotide Accession Number

NM_001238.2XM_006723457.2

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