CCNE1 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
G1/S-specific cyclin-E1
Gene Aliases
CCNE, pCCNE1
Gene ID
898
Swiss Prot
P24864
Accession Number
NP_001229.1XP_006723520.1
Immunogen
Cyclin E1 polyclonal antibody is produced by immunizing rabbit with asynthetic peptide derived from human Cyclin E1
Target
Cyclin E is a regulatory subunit of cdk-2 and controls G1/S transition during the mammalian cell cycle. Multiple isoforms of cyclin E are expressed only in tumors but not in the normal tissues, suggesting a post-transcriptional regulation of cyclin E. In vitro analyses indicated that these truncated variant isoforms of cyclin E are able to phosphorylate histone H1. Alterations in cyclin E protein have been implicated as indicators of worse prognosis in various cancers.
Clonality
Polyclonal
Type
Polyclonal Antibody
Source
Rabbit pAb
Applications
WB
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Reconstitution
Store the product at -20C. Stable for one year from the date of shipment.
Molecular Weight
47 kDa
Fragment
Rabbit lgG
Specificity
Cyclin E1 polyclonal antibody detects endogenous levels of total Cyclin E1 protein
Protein Length
410
NCBI Gene Symbol
CCNE1
Host or Source
Rabbit
Protein Name
G1/S-specific cyclin-E1
Gene Name URL
CCNE1
Nucleotide Accession Number
NM_001238.2XM_006723457.2
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