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STAT3 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Signal transducer and activator of transcription 3

Gene Aliases

APRF, HIES, ADMIO, ADMIO1

Gene ID

6774

Swiss Prot

P40763

Accession Number

NP_003141.2NP_644805.1NP_998827.1XP_005257673.2XP_005257674.2

Reactivity

Human, Mouse, Rat, Chinese hamster, Dog

Immunogen

This Aviva monoclonal antibody is produced by immunizing mice with a recombinant polypeptide (Aviva SEAL mAb technology) corresponding to urface multi-epitopes of human Stat3.

Target

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. Stat3 is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis.

Clonality

Monoclonal

Type

Monoclonal Antibody

Source

Mouse mAb

Applications

WB

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Reconstitution

Store the product at -20C. Stable for one year from the date of shipment.

Molecular Weight

88 kDa

Fragment

Mouse IgG

Specificity

Stat3 monoclonal antibody detects endogenous levels of Stat3 protein.

Protein Length

770

NCBI Gene Symbol

STAT3

Host or Source

Mouse

Protein Name

Signal transducer and activator of transcription 3

Gene Name URL

STAT3

Nucleotide Accession Number

NM_003150.3NM_139276.2NM_213662.1XM_005257616.2XM_005257617.2

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