STAT3 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Signal transducer and activator of transcription 3
Gene Aliases
APRF, HIES, ADMIO, ADMIO1
Gene ID
6774
Swiss Prot
P40763
Accession Number
NP_003141.2NP_644805.1NP_998827.1XP_005257673.2XP_005257674.2
Reactivity
Human, Mouse, Rat, Chinese hamster, Dog
Immunogen
This Aviva monoclonal antibody is produced by immunizing mice with a recombinant polypeptide (Aviva SEAL mAb technology) corresponding to urface multi-epitopes of human Stat3.
Target
The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. Stat3 is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and BMP2. This protein mediates the expression of a variety of genes in response to cell stimuli, and thus plays a key role in many cellular processes such as cell growth and apoptosis.
Clonality
Monoclonal
Type
Monoclonal Antibody
Source
Mouse mAb
Applications
WB
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Reconstitution
Store the product at -20C. Stable for one year from the date of shipment.
Molecular Weight
88 kDa
Fragment
Mouse IgG
Specificity
Stat3 monoclonal antibody detects endogenous levels of Stat3 protein.
Protein Length
770
NCBI Gene Symbol
STAT3
Host or Source
Mouse
Protein Name
Signal transducer and activator of transcription 3
Gene Name URL
STAT3
Nucleotide Accession Number
NM_003150.3NM_139276.2NM_213662.1XM_005257616.2XM_005257617.2
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