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SMARCA4 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Transcription activator BRG1

Gene Aliases

BRG1, CSS4, SNF2, SWI2, MRD16, RTPS2, BAF190, SNF2L4, SNF2LB, hSNF2b, BAF190A, SNF2-beta

Gene ID

6597

Swiss Prot

P51532

Accession Number

NP_001122316.1NP_001122317.1NP_001122318.1NP_001122319.1NP_001122320.1NP_003063.2

Reactivity

Human, Mouse, Rat, Monkey, Chinese hamster, Dog

Immunogen

This Aviva monoclonal antibody is produced by immunizing mice with a peptide corresponding to amino-terminal residues of human Brg1.

Target

This protein encoded by this gene is a member of the SWI/SNF family of proteins and is similar to the brahma protein of Drosophila. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. Brg1 is part of the large ATP-dependent chromatin remodeling complex SNF/SWI, which is required for transcriptional activation of genes normally repressed by chromatin. In addition, this protein can bind BRCA1, as well as regulate the expression of the tumorigenic protein Cd44

Clonality

Monoclonal

Type

Monoclonal Antibody

Source

Mouse mAb

Applications

WB, IF

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Reconstitution

Store the product at -20C. Stable for one year from the date of shipment.

Molecular Weight

188 kDa

Fragment

Mouse IgG

Specificity

Brg1 monoclonal antibody detects endogenous levels of Brg1 protein

Protein Length

1679

NCBI Gene Symbol

SMARCA4

Host or Source

Mouse

Protein Name

Transcription activator BRG1

Gene Name URL

SMARCA4

Nucleotide Accession Number

NM_001128844.1NM_001128845.1NM_001128846.1NM_001128847.1NM_001128848.1NM_003072.3

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