TIMP1 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
TIMP metallopeptidase inhibitor 1
Gene Aliases
EPA, EPO, HCI, CLGI, TIMP, TIMP-1
Gene ID
7076
Swiss Prot
P01033
Accession Number
NP_003245.1
Immunogen
The antiserum was produced against synthesized peptide derived between 80-120 aa of human TIMP1. The exact sequence is proprietary.
Target
This gene belongs to the TIMP gene family. The proteins encoded by this gene family are natural inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix. In addition to its inhibitory role against most of the known MMPs, the encoded protein is able to promote cell proliferation in a wide range of cell types, and may also have an anti-apoptotic function. Transcription of this gene is highly inducible in response to many cytokines and hormones. In addition, the expression from some but not all inactive X chromosomes suggests that this gene inactivation is polymorphic in human females. This gene is located within intron 6 of the synapsin I gene and is transcribed in the opposite direction.
Clonality
Monoclonal
Clone
ABT-TIMP1
Type
Monoclonal Antibody
Applications
IHC-P
Purification
Immunogen affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid. Supplied in 1% BSA, 0.05M Tris-HCl, 0.15M NaCl, 0.2% Kathon CG/ICP, 0.1% Tween-20
Reconstitution
Shipped at 4C. Store at -20C. Stable for 12 months at -20C.
Molecular Weight
23 kDa
Fragment
IgG
Specificity
Anti-Tissue Inhibitor of Metalloproteinases 1 (TIMP1) [ABT-TIMP1] detects endogenous levels of total Tissue Inhibitor of Metalloproteinases 1 (TIMP1) protein.
NCBI Gene Symbol
TIMP1
Host or Source
Mouse
Protein Name
Metalloproteinase inhibitor 1
Gene Name URL
TIMP1
Nucleotide Accession Number
NM_003254.2
Frequently Asked Questions
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