What is the catalog number for VHL Antibody?

The catalog number for VHL Antibody is OAAF08344-100UL.

What sizes are available for VHL Antibody?

VHL Antibody is available in the following size(s): 100 µL.

Is VHL Antibody in stock?

VHL Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

VHL Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Von Hippel-Lindau tumor suppressor

Gene Aliases

RCA1, VHL1, pVHL, HRCA1

Gene ID

7428

Swiss Prot

P40337

Accession Number

NP_000542.1ï»¿

Immunogen

The antiserum was produced against synthesized peptide derived between 170-213 aa of human VHL. The exact sequence is proprietary.

Target

Von Hippel-Lindau syndrome (VHL) is a dominantly inherited familial cancer syndrome predisposing to a variety of malignant and benign tumors. A germline mutation of this gene is the basis of familial inheritance of VHL syndrome. The protein encoded by this gene is a component of the protein complex that includes elongin B, elongin C, and cullin-2, and possesses ubiquitin ligase E3 activity. This protein is involved in the ubiquitination and degradation of hypoxia-inducible-factor (HIF), which is a transcription factor that plays a central role in the regulation of gene expression by oxygen. RNA polymerase II subunit POLR2G/RPB7 is also reported to be a target of this protein. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

Clonality

Monoclonal

Clone

ABT-PVHL

Type

Monoclonal Antibody

Applications

IHC-P

Purification

Immunogen affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol