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PIK3CA Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit alpha

Gene Aliases

MCM, CWS5, MCAP, PI3K, CLAPO, CLOVE, MCMTC, PI3K-alpha, p110-alpha

Gene ID

5290

Swiss Prot

P42336

Accession Number

NP_006209.2

Immunogen

The antiserum was produced against synthesized peptide derived between 1010-1068 aa of human PIK3CA. The exact sequence is proprietary.

Target

Phosphatidylinositol 3-kinase is composed of an 85 kDa regulatory subunit and a 110 kDa catalytic subunit. The protein encoded by this gene represents the catalytic subunit, which uses ATP to phosphorylate PtdIns, PtdIns4P and PtdIns (4,5) P2. This gene has been found to be oncogenic and has been implicated in cervical cancers. A pseudogene of this gene has been defined on chromosome 22.

Clonality

Monoclonal

Clone

ABT-PI3.H1047R

Type

Monoclonal Antibody

Applications

WB, IHC-P

Purification

Immunogen affinity purified

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Format

Liquid. Supplied in 1% BSA, 0.05M Tris-HCl, 0.15M NaCl, 0.2% Kathon CG/ICP, 0.1% Tween-20

Reconstitution

Shipped at 4C. Store at -20C. Stable for 12 months at -20C.

Molecular Weight

124 kDa

Fragment

IgG

Specificity

Anti-PIK3CA H1047R [ABT-PI3.H1047R] detects endogenous levels of total PIK3CA H1047R protein.

NCBI Gene Symbol

PIK3CA

Host or Source

Mouse

Protein Name

Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform

Gene Name URL

PIK3CA

Nucleotide Accession Number

XM_011512894.2

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