GCG Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Glucagon
Gene Aliases
GLP1, GLP2, GRPP, GLP-1
Gene ID
2641
Swiss Prot
P01275
Accession Number
NP_002045.1
Immunogen
The antiserum was produced against synthesized peptide derived between 50-90 aa of human GCG. The exact sequence is proprietary.
Target
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.
Clonality
Monoclonal
Clone
ABT-GCG
Type
Monoclonal Antibody
Applications
IHC-P
Purification
Immunogen affinity purified
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Format
Liquid. Supplied in 1% BSA, 0.05M Tris-HCl, 0.15M NaCl, 0.2% Kathon CG/ICP, 0.1% Tween-20
Reconstitution
Shipped at 4C. Store at -20C. Stable for 12 months at -20C.
Molecular Weight
21 kDa
Fragment
IgG
Specificity
Anti-Glucagon [ABT-GCG] detects endogenous levels of total Glucagon protein.
NCBI Gene Symbol
GCG
Host or Source
Mouse
Protein Name
Glucagon
Gene Name URL
GCG
Nucleotide Accession Number
NM_002054.4
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