CCL4 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
C-C motif chemokine ligand 4|C-C motif chemokine ligand 4 like 1|C-C motif chemokine ligand 4 like 2
Gene Aliases
ACT2; AT744.1; AT744.2; CC chemokine ligand 4L1; C-C motif chemokine 4; C-C motif chemokine 4-like; CCL4L; chemokine (C-C motif) ligand 4; chemokine (C-C motif) ligand 4-like 1, telomeric; chemokine (C-C motif) ligand 4-like 2; G-26; G-26 T-lymphocyte-secreted protein; HC21; LAG1; LAG-1; lymphocyte activation gene 1 protein; macrophage inflammatory protein 1-beta; macrophage inflammatory protein-1b2; MIP1B; MIP1B1; MIP-1-beta; MIP-1-beta (1-69) ; Monocyte adherence-induced protein 5-alpha; PAT 744; Protein H400; SCYA2; SCYA4; SCYA4L; SCYA4L1; SCYA4L2; SCYQ4L2; secreted protein G-26; SIS-gamma; small inducible cytokine A4 (homologous to mouse Mip-1b) ; small inducible cytokine A4-like; Small-inducible cytokine A4; Small-inducible cytokine A4-like; T-cell activation protein 2.
Gene ID
388372|6351|9560
Swiss Prot
P13236
Reactivity
Human|Mouse|Rat
Immunogen
The antiserum was produced against synthesized peptide derived from the Internal region of human CCL4.
Target
Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV) . The processed form MIP-1-beta (3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta (3-69) is also a ligand for CCR1 and CCR2 isoform B.
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
RKLPRNFVVDYYETSSLCSQPAVVFQTKRSKQVCADPSESWVQEYVYDLE
Applications
Enzyme-linked immunosorbent assay|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using peptide.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1mg/ml
Reconstitution
-20°C
Molecular Weight
10 kDa
Specificity
CCL4 Antibody detects endogenous levels of CCL4 protein.
NCBI Gene Symbol
CCL4|CCL4L1|CCL4L2
Host or Source
Rabbit
Protein Name
C-C motif chemokine 4
Gene Name URL
CCL4|CCL4L1|CCL4L2
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