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P73 Antibody (Phospho-Tyr99)

Product Specifications

CAS Number

9007-83-4

Gene Name

Tumor protein p73

Gene Aliases

CILD47; p53-like transcription factor; p53-related protein; P73; tumor protein p73.

Gene ID

7161

Swiss Prot

O15350

Reactivity

Human|Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human p73 around the phosphorylation site of Tyr99.

Target

Participates in the apoptotic response to DNA damage. Isoforms containing the transactivation domain are pro-apoptotic, isoforms lacking the domain are anti-apoptotic and block the function of p53 and transactivating p73 isoforms. May be a tumor suppressor protein.

Clonality

Polyclonal

Type

Polyclonal Antibody

Sequence

NLLSSTMDQMSSRAASASPYTPEHAASVPTHSPYAQPSSTFDTMSPAPVI

Applications

Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1mg/ml

Reconstitution

-20°C

Molecular Weight

69 kDa

Notes

Formerly GWB-ASB778

Specificity

P73 (Phospho-Tyr99) Antibody detects endogenous levels of p73 only when phosphorylated at Tyr99.

NCBI Gene Symbol

TP73

Host or Source

Rabbit

Protein Name

Tumor protein p73

Gene Name URL

TP73

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