KIF2C Antibody (Phospho-Ser95)
Product Specifications
CAS Number
9007-83-4
Gene Name
Kinesin family member 2C
Gene Aliases
CT139; kinesin-like protein 6; kinesin-like protein KIF2C; KNSL6; MCAK; mitotic centromere-associated kinesin; testis tissue sperm-binding protein Li 68n.
Gene ID
11004
Swiss Prot
Q99661
Reactivity
Human|Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human KIF2C around the phosphorylation site of Ser95.
Target
In complex with KIF18B, constitutes the major microtubule plus-end depolymerizing activity in mitotic cells (PubMed:21820309) . Regulates the turnover of microtubules at the kinetochore and functions in chromosome segregation during mitosis (PubMed:19060894) . Plays a role in chromosome congression and is required for the lateral to end-on conversion of the chromosome-microtubule attachment (PubMed:23891108) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
VAAINPELLQLLPLHPKDNLPLQENVTIQKQKRRSVNSKIPAPKESLRSR
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Western blot
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1mg/ml
Reconstitution
-20°C
Molecular Weight
81 kDa
Notes
Formerly GWB-ASB574
Specificity
KIF2C (Phospho-Ser95) Antibody detects endogenous levels of KIF2C only when phosphorylated at Ser95.
NCBI Gene Symbol
KIF2C
Host or Source
Rabbit
Protein Name
Kinesin-like protein KIF2C
Gene Name URL
KIF2C
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