SSB Antibody (Phospho-Ser366)
Product Specifications
CAS Number
9007-83-4
Gene Name
Small RNA binding exonuclease protection factor La
Gene Aliases
Autoantigen La; La; la autoantigen; La ribonucleoprotein; La ribonucleoprotein domain family, member 3; La/SSB; LARP3; lupus La antigen; lupus La protein; sjoegren syndrome type B antigen; Sjogren syndrome antigen B; SS-B; SS-B/La protein.
Gene ID
6741
Swiss Prot
P05455
Reactivity
Human|Mouse|Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human SSB around the phosphorylation site of Ser366.
Target
Binds to the 3' poly (U) terminus of nascent RNA polymerase III transcripts, protecting them from exonuclease digestion and facilitating their folding and maturation (PubMed:3192525, PubMed:2470590) . In case of Coxsackievirus B3 infection, binds to the viral internal ribosome entry site (IRES) and stimulates the IRES-mediated translation (PubMed:12384597) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
KGNKAAQPGSGKGKVQFQGKKTKFASDDEHDEHDENGATGPVKRAREETD
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1mg/ml
Reconstitution
-20°C
Molecular Weight
46 kDa
Notes
Formerly GWB-ASB559
Specificity
SSB (Phospho-Ser366) Antibody detects endogenous levels of SSB only when phosphorylated at Ser366.
NCBI Gene Symbol
SSB
Host or Source
Rabbit
Protein Name
Lupus La protein
Gene Name URL
SSB
Frequently Asked Questions
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