P57 Kip2 Antibody (Phospho-Thr310)
Product Specifications
CAS Number
9007-83-4
Gene Name
Cyclin dependent kinase inhibitor 1C
Gene Aliases
BWCR; BWS; cyclin-dependent kinase inhibitor 1C; cyclin-dependent kinase inhibitor 1C (p57, Kip2) ; cyclin-dependent kinase inhibitor p57; KIP2; p57; p57Kip2; WBS.
Gene ID
1028
Swiss Prot
P49918
Reactivity
Human|Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human p57 Kip2 around the phosphorylation site of Thr310.
Target
Potent tight-binding inhibitor of several G1 cyclin/CDK complexes (cyclin E-CDK2, cyclin D2-CDK4, and cyclin A-CDK2) and, to lesser extent, of the mitotic cyclin B-CDC2. Negative regulator of cell proliferation. May play a role in maintenance of the non-proliferative state throughout life.
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
LSGPLISDFFAKRKRSAPEKSSGDVPAPCPSPSAAPGVGSVEQTPRKRLR
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1mg/ml
Reconstitution
-20°C
Molecular Weight
32 kDa
Notes
Formerly GWB-ASB450
Specificity
P57 Kip2 (Phospho-Thr310) Antibody detects endogenous levels of p57 Kip2 only when phosphorylated at Thr310.
NCBI Gene Symbol
CDKN1C
Host or Source
Rabbit
Protein Name
Cyclin-dependent kinase inhibitor 1C
Gene Name URL
CDKN1C
Frequently Asked Questions
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