Interferon-gamma Receptor alpha Antibody (Phospho-Tyr457)
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Product Specifications
CAS Number
9007-83-4
Gene Name
Interferon gamma receptor 1
Gene Aliases
Antiviral protein, type 2; AVP, type 2; CD119; CD119 antigen; CDw119; IFN-gamma receptor 1; IFN-gamma-R1; IFN-gamma-R-alpha; IFNGR; IMD27A; IMD27B; immune interferon receptor 1; interferon gamma receptor 1; Interferon gamma receptor alpha-chain; interferon-gamma receptor alpha chain.
Gene ID
3459
Swiss Prot
P15260
Reactivity
Human|Monkey|Mouse|Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human Interferon-gamma Receptor alpha around the phosphorylation site of Tyr457.
Target
Associates with IFNGR2 to form a receptor for the cytokine interferon gamma (IFNG) (PubMed:7615558, PubMed:2971451, PubMed:7617032, PubMed:10986460) . Ligand binding stimulates activation of the JAK/STAT signaling pathway (PubMed:7673114) . Plays an essential role in the IFN-gamma pathway that is required for the cellular response to infectious agents (PubMed:20015550) .
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
PPNNKGEIKTEGQELITVIKAPTSFGYDKPHVLVDLLVDDSGKESLIGYR
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1mg/ml
Reconstitution
-20°C
Molecular Weight
54 kDa
Notes
Formerly GWB-ASB446
Specificity
Interferon-gamma Receptor alpha (Phospho-Tyr457) Antibody detects endogenous levels of Interferon-gamma Receptor alpha only when phosphorylated at Tyr457.
NCBI Gene Symbol
IFNGR1
Host or Source
Rabbit
Protein Name
Interferon gamma receptor 1
Gene Name URL
IFNGR1
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