PLC beta3 Antibody (Phospho-Ser537)
Product Specifications
CAS Number
9007-83-4
Gene Name
Phospholipase C beta 3
Gene Aliases
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3; phosphoinositide phospholipase C-beta-3; phospholipase C, beta 3 (phosphatidylinositol-specific) ; Phospholipase C-beta-3; PLC beta 3; SMDCD.
Gene ID
5331
Swiss Prot
Q01970
Reactivity
Human|Mouse|Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human PLC beta3 around the phosphorylation site of Ser537.
Target
The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes.
Clonality
Polyclonal
Type
Polyclonal Antibody
Sequence
PSSPQLGSPSSDSCPGLSNGEEVGLEKPSLEPQKSLGDEGLNRGPYVLGP
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Concentration
1mg/ml
Reconstitution
-20°C
Molecular Weight
138 kDa
Notes
Formerly GWB-ASB300
Specificity
PLC beta3 (Phospho-Ser537) Antibody detects endogenous levels of PLC beta3 only when phosphorylated at Ser537.
NCBI Gene Symbol
PLCB3
Host or Source
Rabbit
Protein Name
1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase beta-3
Gene Name URL
PLCB3
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