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Nicotinic acid riboside

Product Specifications

UNSPSC Description

Nicotinic acid riboside is a NAD+ precursor in human cells. Nicotinic acid riboside is an authentic intermediate of human NAD+ metabolism[1][2].

Target Antigen

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/nicotinic-acid-riboside.html

Purity

99.79

Solubility

H2O : 62.5 mg/mL (ultrasonic)

Smiles

[O-]C(C1=C[N+]([C@@H]2O[C@@H]([C@H]([C@H]2O)O)CO)=CC=C1)=O

Molecular Weight

255.226

References & Citations

[1]Sasaki Y, et al. Nicotinic acid mononucleotide is an allosteric SARM1 inhibitor promoting axonal protection. Exp Neurol. 2021;345:113842.|[2]Bogan KL, et al. Identification of Isn1 and Sdt1 as glucose- and vitamin-regulated nicotinamide mononucleotide and nicotinic acid mononucleotide [corrected] 5'-nucleotidases responsible for production of nicotinamide riboside and nicotinic acid riboside [published correction appears in J Biol Chem. 2010 Jan 29;285(5):3524]. J Biol Chem. 2009;284(50):34861-34869.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-W104368/Nicotinic-acid-riboside-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-W104368/Nicotinic-acid-riboside-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

17720-18-2

Available Sizes

Curated Selection

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