Nicotinic acid riboside

Nicotinic acid riboside is a NAD+ precursor in human cells. Nicotinic acid riboside is an authentic intermediate of human NAD+ metabolism[1][2].

Product Specifications

CAS Number

[17720-18-2]

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Natural Products

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Cancer; Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/nicotinic-acid-riboside.html

Purity

99.90

Solubility

H2O : 62.5 mg/mL (ultrasonic)

Smiles

[O-]C(C1=C[N+]([C@@H]2O[C@@H]([C@H]([C@H]2O)O)CO)=CC=C1)=O

Molecular Formula

C11H13NO6

Molecular Weight

255.23

Precautions

H302, H315, H319, H335

References & Citations

[1]Sasaki Y, et al. Nicotinic acid mononucleotide is an allosteric SARM1 inhibitor promoting axonal protection. Exp Neurol. 2021;345:113842.|[2]Bogan KL, et al. Identification of Isn1 and Sdt1 as glucose- and vitamin-regulated nicotinamide mononucleotide and nicotinic acid mononucleotide [corrected] 5'-nucleotidases responsible for production of nicotinamide riboside and nicotinic acid riboside [published correction appears in J Biol Chem. 2010 Jan 29;285 (5) :3524]. J Biol Chem. 2009;284 (50) :34861-34869.