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Erbin Antibody (Phospho-Tyr1104)

Product Specifications

CAS Number

9007-83-4

Gene Name

Erbb2 interacting protein

Gene Aliases

Densin-180-like protein; epididymis secretory protein Li 78; Erbb2-interacting protein; ERBB2IP; erbin; HEL-S-78; LAP2; protein LAP2.

Gene ID

55914

Swiss Prot

Q96RT1

Reactivity

Human|Mouse|Rat

Immunogen

The antiserum was produced against synthesized phospho-peptide derived from human Erbin around the phosphorylation site of Tyr1104.

Target

Acts as an adapter for the receptor ERBB2, in epithelia. By binding the unphosphorylated 'Tyr-1248' of receptor ERBB2, it may contribute to stabilize this unphosphorylated state (PubMed:16203728) . Inhibits NOD2-dependent NF-kappa-B signaling and proinflammatory cytokine secretion (PubMed:16203728) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Western blot

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific phosphopeptide. The antibody against non-phosphopeptide was removed by chromatography using non-phosphopeptide corresponding to the phosphorylation.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Reconstitution

-20°C

Molecular Weight

158 kDa

Specificity

Erbin (Phospho-Tyr1104) antibody detects endogenous levels of Erbin only when phosphorylated at Tyr1104.

NCBI Gene Symbol

ERBIN

Host or Source

Rabbit

Protein Name

Erbin

Gene Name URL

ERBIN

Frequently Asked Questions

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