Casp6 (Cleaved-Asp162) Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Caspase 6

Gene Aliases

Apoptotic protease Mch-2; CASP-6; caspase-6; mCAS; Mch2.

Gene ID

12368

Swiss Prot

O08738

Accession Number

NP_033941.3

Reactivity

Mouse|Rat

Immunogen

The antiserum was produced against synthesized peptide derived from mouse Caspase 6. AA range: 144-193

Target

Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves poly (ADP-ribose) polymerase in vitro, as well as lamins. Overexpression promotes programmed cell death (By similarity) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Concentration

1 mg/ml

Dilution

The optimal working dilution should be determined by the end user.

Format

Liquid.//PBS with 0.5% BSA, 0.02% sodium azide and 50% glycerol.

Reconstitution

Store at -20° C for 1 year.

Molecular Weight

28 and 35 kDa

Notes

Formerly GWB-ASF676

Fragment

IgG

Specificity

Cleaved-Caspase-6 p18 (D162) Polyclonal antibody detects endogenous levels of fragment of activated Caspase-6 p18 protein resulting from cleavage adjacent to D162.