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BAI1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Adhesion G protein-coupled receptor B1

Gene Aliases

Adhesion G protein-coupled receptor B1; BAI1; brain-specific angiogenesis inhibitor 1; GDAIF.

Gene ID

575

Swiss Prot

O14514

Accession Number

NP_001693.2

Reactivity

Human|Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human BAI1.

Target

Phosphatidylserine receptor which enhances the engulfment of apoptotic cells (PubMed:24509909) . Also mediates the binding and engulfment of Gram-negative bacteria (PubMed:26838550) . Stimulates production of reactive oxygen species by macrophages in response to Gram-negative bacteria, resulting in enhanced microbicidal macrophage activity (PubMed:26838550) . In the gastric mucosa, required for recognition and engulfment of apoptotic gastric epithelial cells (PubMed:24509909) . Promotes myoblast fusion (By similarity) . Activates the Rho pathway in a G-protein-dependent manner (PubMed:23782696) . Inhibits MDM2-mediated ubiquitination and degradation of DLG4/PSD95, promoting DLG4 stability and regulating synaptic plasticity (By similarity) . Required for the formation of dendritic spines by ensuring the correct localization of PARD3 and TIAM1 (By similarity) . Potent inhibitor of angiogenesis in brain and may play a significant role as a mediator of the p53/TP53 signal in suppression of glioblastoma (PubMed:11875720) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Dilution

The optimal working dilution should be determined by the end user.

Format

Liquid

Reconstitution

-20°C

Molecular Weight

173 kDa

Notes

Formerly GWB-ASF258

Specificity

BAI1 antibody detects endogenous levels of total BAI1 protein.

NCBI Gene Symbol

ADGRB1

Host or Source

Rabbit

Protein Name

Adhesion G protein-coupled receptor B1

Gene Name URL

ADGRB1

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