What is the catalog number for PPP4R2 Antibody?

The catalog number for PPP4R2 Antibody is OAAF04268-100UG.

What sizes are available for PPP4R2 Antibody?

PPP4R2 Antibody is available in the following size(s): 100 µg.

Is PPP4R2 Antibody in stock?

PPP4R2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

PPP4R2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Protein phosphatase 4 regulatory subunit 2

Gene Aliases

PP4R2; serine/threonine-protein phosphatase 4 regulatory subunit 2.

Gene ID

151987

Swiss Prot

Q9NY27

Accession Number

NP_777567.1

Reactivity

Human|Monkey

Immunogen

The antiserum was produced against synthesized peptide derived from human PPP4R2.

Target

Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4) . May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA double strand break repair. Mediates RPA2 dephosphorylation by recruiting PPP4C to RPA2 in a DNA damage-dependent manner. RPA2 dephosphorylation is required for the efficient RPA2-mediated recruitment of RAD51 to chromatin following double strand breaks, an essential step for DNA repair.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Dilution

The optimal working dilution should be determined by the end user.

Format

Liquid

Reconstitution

-20°C

Molecular Weight

46 kDa

Notes

Formerly GWB-ASF000

Specificity

PP4R2 antibody detects endogenous levels of total PP4R2 protein.

NCBI Gene Symbol

PPP4R2

Host or Source

Rabbit

Protein Name

Serine/threonine-protein phosphatase 4 regulatory subunit 2

Gene Name URL

PPP4R2

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