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HCN2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Hyperpolarization activated cyclic nucleotide gated potassium and sodium channel 2

Gene Aliases

BCNG2; BCNG-2; brain cyclic nucleotide-gated channel 2; EIG17; FEB2; GEFSP11; HAC-1; hyperpolarization activated cyclic nucleotide gated potassium channel 2; potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2.

Gene ID

610

Swiss Prot

Q9UL51

Accession Number

NP_001185.3

Reactivity

Human|Mouse|Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human HCN2.

Target

Hyperpolarization-activated ion channel exhibiting weak selectivity for potassium over sodium ions. Contributes to the native pacemaker currents in heart (If) and in neurons (Ih) . Can also transport ammonium in the distal nephron. Produces a large instantaneous current. Modulated by intracellular chloride ions and pH; acidic pH shifts the activation to more negative voltages (By similarity) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Dilution

The optimal working dilution should be determined by the end user.

Format

Liquid

Reconstitution

-20°C

Molecular Weight

96 kDa

Notes

Formerly GWB-ASE858

Specificity

HCN2 antibody detects endogenous levels of total HCN2 protein.

NCBI Gene Symbol

HCN2

Host or Source

Rabbit

Protein Name

Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2

Gene Name URL

HCN2

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