MBTPS2 Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Membrane bound transcription factor peptidase, site 2
Gene Aliases
BRESEK; endopeptidase S2P; IFAP; keratosis follicularis spinulosa decalvans; KFSD; KFSDX; membrane-bound transcription factor protease, site 2; membrane-bound transcription factor site-2 protease; OI19; OLMSX; S2P; site-2 protease; SREBPs intramembrane protease; sterol regulatory element-binding proteins intramembrane protease.
Gene ID
51360
Swiss Prot
O43462
Accession Number
NP_056968.1
Reactivity
Human|Mouse|Rat
Immunogen
The antiserum was produced against synthesized peptide derived from human MBTPS2.
Target
Intramembrane proteolysis of sterol-regulatory element-binding proteins (SREBPs) within the first transmembrane segment thereby releasing the N-terminal segment with a portion of the transmembrane segment attached. Site-2 cleavage comes after site-1 cleavage which takes place in the lumenal loop.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
57 kDa
Notes
Formerly GWB-ASE701
Specificity
MBTPS2 antibody detects endogenous levels of total MBTPS2 protein.
NCBI Gene Symbol
MBTPS2
Host or Source
Rabbit
Protein Name
Membrane-bound transcription factor site-2 protease
Gene Name URL
MBTPS2
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