DHRS11 Antibody
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Product Specifications
CAS Number
9007-83-4
Gene Name
Dehydrogenase/reductase 11
Gene Aliases
17-beta-hydroxysteroid dehydrogenase;3-beta-hydroxysteroid 3-dehydrogenase; ARPG836; dehydrogenase/reductase (SDR family) member 11; dehydrogenase/reductase SDR family member 11; estradiol 17-beta-dehydrogenase; SDR24C1; short-chain dehydrogenase/reductase family 24C member 1; spDHRS11.
Gene ID
79154
Swiss Prot
Q6UWP2
Accession Number
NP_077284.2
Reactivity
Human|Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human DHRS11.
Target
Catalyzes the conversion of the 17-keto group of estrone, 4- and 5-androstenes and 5-alpha-androstanes into their 17-beta-hydroxyl metabolites and the conversion of the 3-keto group of 3-, 3,17- and 3,20- diketosteroids into their 3-hydroxyl metabolites. Exhibits reductive 3-beta-hydroxysteroid dehydrogenase activity toward 5-beta-androstanes, 5-beta-pregnanes, 4-pregnenes and bile acids. May also reduce endogenous and exogenous alpha-dicarbonyl compounds and xenobiotic alicyclic ketones.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
28 kDa
Notes
Formerly GWB-ASE521
Specificity
DHRS11 antibody detects endogenous levels of total DHRS11 protein.
NCBI Gene Symbol
DHRS11
Host or Source
Rabbit
Protein Name
Dehydrogenase/reductase SDR family member 11
Gene Name URL
DHRS11
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