What is the catalog number for PRKAG2 Antibody?

The catalog number for PRKAG2 Antibody is OAAF02723-100UG.

What sizes are available for PRKAG2 Antibody?

PRKAG2 Antibody is available in the following size(s): 100 µg.

Is PRKAG2 Antibody in stock?

PRKAG2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

PRKAG2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Protein kinase AMP-activated non-catalytic subunit gamma 2

Gene Aliases

5'-AMP-activated protein kinase subunit gamma-2; AAKG; AAKG2; AMPK subunit gamma-2; CMH6; epididymis secretory sperm binding protein; H91620p; protein kinase, AMP-activated, gamma 2 non-catalytic subunit; WPWS.

Gene ID

51422

Swiss Prot

Q9UGJ0

Accession Number

NP_001035723.1

Reactivity

Human|Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human PRKAG2.

Target

AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol