What is the catalog number for KSR2 Antibody?

The catalog number for KSR2 Antibody is OAAF02508-100UG.

What sizes are available for KSR2 Antibody?

KSR2 Antibody is available in the following size(s): 100 µg.

Is KSR2 Antibody in stock?

KSR2 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

KSR2 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Kinase suppressor of ras 2

Gene Aliases

Kinase suppressor of Ras 2.

Gene ID

283455

Swiss Prot

Q6VAB6

Accession Number

NP_775869.3

Reactivity

Human|Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human KSR2.

Target

Location-regulated scaffold connecting MEK to RAF. Has very low protein kinase activity and can phosphorylate MAP2K1 at several Ser and Thr residues with very low efficiency (in vitro) . Interaction with BRAF enhances KSR2-mediated phosphorylation of MAP2K1 (in vitro) . Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol