What is the catalog number for ZFHX3 Antibody?

The catalog number for ZFHX3 Antibody is OAAF02469-100UG.

What sizes are available for ZFHX3 Antibody?

ZFHX3 Antibody is available in the following size(s): 100 µg.

Is ZFHX3 Antibody in stock?

ZFHX3 Antibody is currently made to order / not held in immediate stock. Contact us for lead time.

ZFHX3 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Zinc finger homeobox 3

Gene Aliases

Alpha-fetoprotein enhancer binding protein; Alpha-fetoprotein enhancer-binding protein; AT motif-binding factor 1; ATBF1; AT-binding transcription factor 1; ATBT; C16orf47; ZFH-3; zinc finger homeobox protein 3; zinc finger homeodomain protein 3; ZNF927.

Gene ID

463

Swiss Prot

Q15911

Accession Number

NP_001158238.1

Reactivity

Human|Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human ZFHX3.

Target

Transcriptional regulator which can act as an activator or a repressor. Inhibits the enhancer element of the AFP gene by binding to its AT-rich core sequence. In concert with SMAD-dependent TGF-beta signaling can repress the transcription of AFP via its interaction with SMAD2/3 (PubMed:25105025) . Regulates the circadian locomotor rhythms via transcriptional activation of neuropeptidergic genes which are essential for intercellular synchrony and rhythm amplitude in the suprachiasmatic nucleus (SCN) of the brain (By similarity) . Regulator of myoblasts differentiation through the binding to the AT-rich sequence of MYF6 promoter and promoter repression (PubMed:11312261) . Down-regulates the MUC5AC promoter in gastric cancer (PubMed:17330845) . In association with RUNX3, upregulates CDKN1A promoter activity following TGF-beta stimulation (PubMed:20599712) . Inhibits estrogen receptor (ESR1) function by selectively competing with coactivator NCOA3 for binding to ESR1 in ESR1-positive breast cancer cells (PubMed:20720010) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry-Paraffin

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol