SOX18 Antibody

CMD1; CMPD1; HLTRS; HLTS; SRA1; SRXX2; SRXY10; SRY (sex determining region Y) -box 17; SRY (sex determining region Y) -box 18; SRY (sex determining region Y) -box 8; SRY (sex determining region Y) -box9; SRY (sex-determining region Y) -box 9 protein; SRY-box 17; SRY-box 18; SRY-box 8; SRY-box 9; SRY-related HMG-box transcription factor SOX17; SRY-related HMG-box, gene 9; transcription factor SOX-17; transcription factor SOX-18; transcription factor SOX-8; transcription factor SOX-9; VUR3.

Acts as transcription regulator that binds target promoter DNA and bends the DNA. Binds to the sequences 5'-AACAAT-'3 or 5'-AACAAAG-3'. Modulates transcriptional regulation via WNT3A. Inhibits Wnt signaling. Promotes degradation of activated CTNNB1. Plays a key role in the regulation of embryonic development. Required for normal looping of the embryonic heart tube. Required for normal development of the definitive gut endoderm. Probable transcriptional activator in the premeiotic germ cells (By similarity) .|Binds to the consensus sequence 5'-AACAAAG-3' and is able to trans-activate transcription via this site.|May play a role in central nervous system, limb and facial development. May be involved in male sex determination. Binds the consensus motif 5'-[AT][AT]CAA[AT]G-3' (By similarity) .|Transcriptional regulator (PubMed:24038782) . Binds to the COL2A1 promoter and activates COL2A1 expression, as part of a complex with ZNF219 (By similarity) . Plays a role in chondrocyte differentiation (By similarity) . Important for normal skeletal development (PubMed:24038782) .

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol