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CIT Antibody

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Product Specifications

CAS Number

9007-83-4

Gene Name

Citron rho-interacting serine/threonine kinase

Gene Aliases

CITK; citron (rho-interacting, serine/threonine kinase 21) ; citron Rho-interacting kinase; CRIK; MCPH17; serine/threonine kinase 21; serine/threonine-protein kinase 21; STK21.

Gene ID

11113

Swiss Prot

O14578

Accession Number

NP_001193928.1

Reactivity

Human|Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human CTRO.

Target

Plays a role in cytokinesis. Required for KIF14 localization to the central spindle and midbody. Putative RHO/RAC effector that binds to the GTP-bound forms of RHO and RAC1. It probably binds p21 with a tighter specificity in vivo. Displays serine/threonine protein kinase activity. Plays an important role in the regulation of cytokinesis and the development of the central nervous system. Phosphorylates MYL9/MLC2.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Dilution

The optimal working dilution should be determined by the end user.

Format

Liquid

Reconstitution

-20°C

Molecular Weight

231 kDa

Notes

Formerly GWB-ASD274

Specificity

CTRO antibody detects endogenous levels of total CTRO protein.

NCBI Gene Symbol

CIT

Host or Source

Rabbit

Protein Name

Citron Rho-interacting kinase

Gene Name URL

CIT

Frequently Asked Questions

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