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NRAS Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

HRas proto-oncogene, GTPase|KRAS proto-oncogene, GTPase|NRAS proto-oncogene, GTPase

Gene Aliases

ALPS4; C-BAS/HAS; cellular c-Ki-ras2 proto-oncogene; cellular transforming proto-oncogene; CFC2; C-HA-RAS1; c-has/bas p21 protein; C-H-RAS; c-Ki-ras; c-Ki-ras2; c-Kirsten-ras protein; C-K-RAS; 'C-K-RAS; CMNS; CTLO; GTP- and GDP-binding peptide B; GTPase HRas; GTPase KRas; GTPase NRas; HAMSV; Ha-Ras; Ha-Ras1 proto-oncoprotein; Harvey rat sarcoma viral oncogene homolog; Harvey rat sarcoma viral oncoprotein; H-Ras-1; HRAS1; H-RASIDX; KI-RAS; Kirsten rat sarcoma viral oncogene homolog; Kirsten rat sarcoma viral proto-oncogene; K-Ras; K-Ras 2; K-ras p21 protein; KRAS1; KRAS2; K-RAS2A; K-RAS2B; K-RAS4A; K-RAS4B; NCMS; neuroblastoma RAS viral (v-ras) oncogene homolog; neuroblastoma RAS viral oncogene homolog; N-ras; N-ras protein part 4; NRAS1; NS; NS3; NS6; OES; oncogene KRAS2; p19 H-RasIDX protein; p21ras; PR310 c-K-ras oncogene; RALD; Ras family small GTP binding protein H-Ras; RASH1; RASK2; transformation gene: oncogene HAMSV; transforming protein N-Ras; transforming protein p21; v-Ha-ras Harvey rat sarcoma viral oncogene homolog; v-Ki-ras2 Kirsten rat sarcoma 2 viral oncogene homolog; v-ras neuroblastoma RAS viral oncogene homolog.

Gene ID

3265|3845|4893

Swiss Prot

P01111|P01112|P01116

Accession Number

NP_004976.2

Reactivity

Human|Mouse|Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human RASH/RASK.

Target

Involved in the activation of Ras protein signal transduction (PubMed:22821884) . Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:12740440, PubMed:14500341, PubMed:9020151) .|Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (PubMed:20949621) . Plays an important role in the regulation of cell proliferation (PubMed:23698361, PubMed:22711838) . Plays a role in promoting oncogenic events by inducing transcriptional silencing of tumor suppressor genes (TSGs) in colorectal cancer (CRC) cells in a ZNF304-dependent manner (PubMed:24623306) .|Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Dilution

The optimal working dilution should be determined by the end user.

Format

Liquid

Reconstitution

-20°C

Molecular Weight

21 kDa

Notes

Formerly GWB-ASD183

Specificity

RASH/RASK/RASN antibody detects endogenous levels of total RASH/RASK/RASN protein.

NCBI Gene Symbol

HRAS|KRAS|NRAS

Host or Source

Rabbit

Protein Name

GTPase HRas|GTPase KRas|GTPase NRas

Gene Name URL

HRAS|KRAS|NRAS

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