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MAGEA1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

MAGE family member A1

Gene Aliases

Antigen MZ2-E; cancer/testis antigen 1.1; cancer/testis antigen family 1, member 1; CT1.1; MAGE1; MAGE-1 antigen; melanoma antigen family A 1; melanoma antigen family A, 1 (directs expression of antigen MZ2-E) ; melanoma antigen family A1; melanoma antigen MAGE-1; melanoma-associated antigen 1; melanoma-associated antigen MZ2-E.

Gene ID

4100

Swiss Prot

P43355

Accession Number

NP_004979.3

Reactivity

Human|Mouse|Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human MAGE-1.

Target

May be involved in transcriptional regulation through interaction with SNW1 and recruiting histone deactelyase HDAC1. May inhibit notch intracellular domain (NICD) transactivation. May play a role in embryonal development and tumor transformation or aspects of tumor progression. Antigen recognized on a melanoma by autologous cytolytic T-lymphocytes.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Dilution

The optimal working dilution should be determined by the end user.

Format

Liquid

Reconstitution

-20°C

Molecular Weight

34 kda

Notes

Formerly GWB-ASD127

Specificity

MAGE-1 antibody detects endogenous levels of total MAGE-1 protein.

NCBI Gene Symbol

MAGEA1

Host or Source

Rabbit

Protein Name

Melanoma-associated antigen 1|Tumor antigen MAGE-N

Gene Name URL

MAGEA1

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