IL4R Antibody
Product Specifications
CAS Number
9007-83-4
Gene Name
Interleukin 4 receptor
Gene Aliases
CD124; IL-4 receptor subunit alpha; IL4R nirs variant 1; IL4RA; IL-4RA; interleukin 13 receptor; interleukin-4 receptor alpha chain; interleukin-4 receptor subunit alpha.
Gene ID
3566
Swiss Prot
P24394
Accession Number
NP_000409.1
Reactivity
Human|Mouse
Immunogen
The antiserum was produced against synthesized peptide derived from human IL-4R/CD124.
Target
Receptor for both interleukin 4 and interleukin 13. Couples to the JAK1/2/3-STAT6 pathway. The IL4 response is involved in promoting Th2 differentiation. The IL4/IL13 responses are involved in regulating IgE production and, chemokine and mucus production at sites of allergic inflammation. In certain cell types, can signal through activation of insulin receptor substrates, IRS1/IRS2.
Clonality
Polyclonal
Type
Polyclonal Antibody
Applications
Enzyme-linked immunosorbent assay|Immunocytochemistry|Immunofluorescence|Western blot
Purification
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Assay Protocol
Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions
Reconstitution & Storage Instructions
Western Blotting/Immunoblotting (WB/IB) Protocol
Western Blotting/Immunoblotting (WB/IB) Protocol
Immunohistochemistry (IHC) Protocol
Immunohistochemistry (IHC) Protocol
Immunocytochemistry (ICC) Protocol
Immunocytochemistry (ICC) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol
Blocking Peptide Competition Protocol (BPCP)
Blocking Peptide Competition Protocol (BPCP)
Immunoprecipitation (IP) Protocol
Immunoprecipitation (IP) Protocol
Antibody Array (AA) Protocol
Antibody Array (AA) Protocol
Dilution
The optimal working dilution should be determined by the end user.
Format
Liquid
Reconstitution
-20°C
Molecular Weight
89 kDa
Notes
Formerly GWB-ASC522
Specificity
IL-4R/CD124 (Ab-497) antibody detects endogenous levels of total IL-4R/CD124 protein.
NCBI Gene Symbol
IL4R
Host or Source
Rabbit
Protein Name
Interleukin-4 receptor subunit alpha
Gene Name URL
IL4R
Curated Selection
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