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SYT1 Antibody

Product Specifications

CAS Number

9007-83-4

Gene Name

Synaptotagmin 1|synaptotagmin 2

Gene Aliases

BAGOS; CMS7; CMS7A; CMS7B; MYSPC; P65; SVP65; synaptotagmin I; synaptotagmin II; synaptotagmin-1; synaptotagmin-2; SYT; sytI; SytII.

Gene ID

127833|6857

Swiss Prot

P21579|Q8N9I0

Accession Number

NP_001129277.1

Reactivity

Human|Mouse|Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Synaptotagmin.

Target

Exhibits calcium-dependent phospholipid and inositol polyphosphate binding properties (By similarity) . May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse (By similarity) . Plays a role in dendrite formation by melanocytes (PubMed:23999003) .|May have a regulatory role in the membrane interactions during trafficking of synaptic vesicles at the active zone of the synapse. It binds acidic phospholipids with a specificity that requires the presence of both an acidic head group and a diacyl backbone. A Ca (2+) -dependent interaction between synaptotagmin and putative receptors for activated protein kinase C has also been reported. It can bind to at least three additional proteins in a Ca (2+) -independent manner; these are neurexins, syntaxin and AP2. Plays a role in dendrite formation by melanocytes (PubMed:23999003) .

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Dilution

The optimal working dilution should be determined by the end user.

Format

Liquid

Reconstitution

-20°C

Molecular Weight

47 kDa

Notes

Formerly GWB-ASC063

Specificity

Synaptotagmin (Ab-309) antibody detects endogenous levels of total Synaptotagmin protein.

NCBI Gene Symbol

SYT1|SYT2

Host or Source

Rabbit

Protein Name

Synaptotagmin-1|Synaptotagmin-2

Gene Name URL

SYT1|SYT2

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