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HIST1H2AB Antibody (Phospho-Thr121)

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Product Specifications

CAS Number

9007-83-4

Gene Name

H2A clustered histone 11|H2A clustered histone 12|H2A clustered histone 13|H2A clustered histone 15|H2A clustered histone 16|H2A clustered histone 17

Gene Aliases

DJ193B12.1; dJ193B12.9; dJ86C11.1; H2A; H2A histone family member; H2A histone family, member A; H2A histone family, member C; H2A histone family, member D; H2A histone family, member G; H2A histone family, member I; H2A histone family, member M; H2A histone family, member N; H2A histone family, member O; H2A histone family, member P; H2A.1; H2A.1b; H2A.2; H2A.3; H2A.i; H2A/a; H2A/c; H2A/d; H2A/g; H2A/i; H2A/m; H2A/n; H2A/O; H2A/p; H2A/q; H2A/R; H2A/S; H2a-615; H2AC11; H2AC13; H2AC14; H2AC15; H2AC16; H2AC17; H2AC18; H2AC19; H2AC4; H2AC8; H2A-clustered histone 18; H2A-clustered histone 19; H2AFA; H2AFALii; H2AFC; H2AFD; H2AFG; H2AFI; H2AFM; H2AFN; H2AFO; H2AFP; H2AG; H2AH; HIST1H2AB; HIST1H2AD; HIST1H2AE; HIST1H2AG; HIST1H2AH; HIST1H2AI; HIST1H2AK; HIST1H2AL; HIST1H2AM; HIST2H2AA; HIST2H2AA3; HIST2H2AA4; HIST3H2A; histone 1, H2ab; histone 1, H2ad; histone 1, H2ae; histone 1, H2ag; histone 1, H2ai; histone 1, H2ak; histone 1, H2al; histone 1, H2am; histone 2, H2aa3; histone 2, H2aa4; histone 3, H2a; histone cluster 1 H2A family member b; histone cluster 1 H2A family member d; histone cluster 1 H2A family member e; histone cluster 1 H2A family member g; histone cluster 1 H2A family member h; histone cluster 1 H2A family member i; histone cluster 1 H2A family member k; histone cluster 1 H2A family member l; histone cluster 1 H2A family member m; histone cluster 1, H2ab; histone cluster 1, H2ad; histone cluster 1, H2ae; histone cluster 1, H2ag; histone cluster 1, H2ah; histone cluster 1, H2ai; histone cluster 1, H2ak; histone cluster 1, H2al; histone cluster 1, H2am; histone cluster 2 H2A family member a3; histone cluster 2 H2A family member a4; histone cluster 2, H2aa3; histone cluster 2, H2aa4; histone cluster 3 H2A; histone cluster 3, H2a; histone H2A type 1; histone H2A type 1-B/E; histone H2A type 1-D; histone H2A type 1-H; histone H2A type 1-J; histone H2A type 2-A; histone H2A type 3; Histone H2A.2; histone H2A.3; histone H2A/a; histone H2A/g; histone H2A/m; Histone H2A/o; histone H2A/p; histone H2A/ptl; histone H2A/r; histone H2A/s; histone H2AD; histone H2AE; pH2A/f.

Gene ID

3012|3013|723790|8329|8330|8332|8335|8336|8337|85235|8969|92815

Swiss Prot

P04908|P0C0S8|P20671|Q6FI13|Q7L7L0|Q96KK5

Accession Number

NP_254280.1

Reactivity

Human|Mouse|Rat

Immunogen

The antiserum was produced against synthesized peptide derived from human Histone H2A around the phosphorylation site of Thr121.

Target

Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin|Western blot

Purification

The antibody was purified from rabbit antiserum by affinity-chromatography using phospho peptide. The antibody against non-phospho peptide was removed by chromatography using corresponding non-phospho peptide.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol

Dilution

The optimal working dilution should be determined by the end user.

Format

Liquid

Reconstitution

-20°C

Molecular Weight

14 kDa

Notes

Formerly GWB-ASB952

Specificity

Histone H2A (Phospho-Thr121) antibody detects endogenous levels of Histone H2A only when phosphorylated at threonine 121.

NCBI Gene Symbol

H2AC11|H2AC12|H2AC13|H2AC15|H2AC16|H2AC17|H2AC18|H2AC19|H2AC4|H2AC7|H2AC8|H2AW

Host or Source

Rabbit

Protein Name

Histone H2A type 1|Histone H2A type 1-B/E|Histone H2A type 1-D|Histone H2A type 1-H|Histone H2A type 2-A|Histone H2A type 3

Gene Name URL

H2AC11|H2AC12|H2AC13|H2AC15|H2AC16|H2AC17|H2AC18|H2AC19|H2AC4|H2AC7|H2AC8|H2AW

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