What is the catalog number for MAP3K9/MAP3K10 Antibody (Bi-Phospho-Thr312/266)?

The catalog number for MAP3K9/MAP3K10 Antibody (Bi-Phospho-Thr312/266) is OAAF00460-100UG.

What sizes are available for MAP3K9/MAP3K10 Antibody (Bi-Phospho-Thr312/266)?

MAP3K9/MAP3K10 Antibody (Bi-Phospho-Thr312/266) is available in the following size(s): 100 µg.

Is MAP3K9/MAP3K10 Antibody (Bi-Phospho-Thr312/266) in stock?

MAP3K9/MAP3K10 Antibody (Bi-Phospho-Thr312/266) is currently made to order / not held in immediate stock. Contact us for lead time.

Do you offer bulk or custom quantities of this product?

Yes. Ordering two or more units, or combining this with other products, usually qualifies for a discount depending on quantity. Contact our sales team with your required volume for a custom quote.

Do you provide a Certificate of Analysis (CoA) for this product?

A Certificate of Analysis is available for most products upon request. Contact our support team with the lot number to obtain the relevant CoA.

Is this product suitable for live cell imaging?

Suitability for live cell imaging depends on the specific reagent and conjugate used. Check the datasheet for imaging-specific validation, or contact us for guidance.

MAP3K9/MAP3K10 Antibody (Bi-Phospho-Thr312/266)

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Product Specifications

CAS Number

9007-83-4

Gene Name

Mitogen-activated protein kinase kinase kinase 10|mitogen-activated protein kinase kinase kinase 9

Gene Aliases

MEKK10; MEKK9; mitogen-activated protein kinase kinase kinase 10; mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; mixed lineage kinase 1 (tyr and ser/thr specificity) ; mixed lineage kinase 2; MKN28 derived nonreceptor_type serine/threonine kinase; MKN28 kinase; MLK1; MLK2; MST; PRKE1; protein kinase MST.

Gene ID

4293|4294

Swiss Prot

P80192|Q02779

Accession Number

NP_002437.2

Reactivity

Human|Mouse

Immunogen

The antiserum was produced against synthesized peptide derived from human MLK1/2 around the phosphorylation site of Thr312/266.

Target

Activates the JUN N-terminal pathway.|Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis.

Clonality

Polyclonal

Type

Polyclonal Antibody

Applications

Enzyme-linked immunosorbent assay|Immunofluorescence|Immunohistochemistry|Immunohistochemistry-Paraffin

Purification

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Assay Protocol

Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Reconstitution & Storage Instructions Reconstitution & Storage Instructions Western Blotting/Immunoblotting (WB/IB) Protocol Western Blotting/Immunoblotting (WB/IB) Protocol Immunohistochemistry (IHC) Protocol Immunohistochemistry (IHC) Protocol Immunocytochemistry (ICC) Protocol Immunocytochemistry (ICC) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Enzyme-Linked ImmunoSorbent Assay (ELISA) Protocol Blocking Peptide Competition Protocol (BPCP) Blocking Peptide Competition Protocol (BPCP) Immunoprecipitation (IP) Protocol Immunoprecipitation (IP) Protocol Antibody Array (AA) Protocol Antibody Array (AA) Protocol